https://www.selleckchem.com/pr....oducts/trometamol.ht
Since the Limk1 is a promising drug target and few inhibitors with good Limk1/ROCK2 selectivity have been reported, discovering potential and selective Limk1 inhibitors with novel scaffolds is becoming an urgent need to develop new treatments for the related diseases. Here, we utilized molecular docking to screen potential compounds of Limk1 from Traditional Chinese Medicine (TCM) database. Meanwhile, we performed a three-dimensional graph convolutional network (3DGCN), based on 3D molecular graph, to predict the inhibitory activity
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