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MATERIALS AND METHODS Major closure associated with extraction socket had been done with a mucoperiosteal flap and two-layer suturing or PRF had been inserted in to the extraction plug without subsequent main closure. In every clients, intra- and postoperative complications plus the general treatment result were recorded. RESULTS The patient sample contained 77 customers; major closing with a mucoperiosteal flap had been carried out in 39 clients (group A), and application of PRF without subsequent primary