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Conclusion The nucleos(t)ide analogs are all effective for HBeAg seroconversion, HBeAg loss, undetectable HBV DNA and most are effective for ALT normalization in adults with CHB. RCTs of multi-center, low risk of bias and long-term follow-up are still needed.Introduction Methicillin-resistant Staphylococcus aureus (MRSA) is associated with adverse clinical outcomes and increased morbidity, mortality, length of hospital stay and health care costs. Rapid diagnosis of MRSA infections has been associated with positive impact on clinical outcom