https://www.selleckchem.com/pr....oducts/LY2228820.htm
Classical MANOVA tests do not pose any difficulty when the assumptions on which they are based are satisfied, while the modified Brown-Forsythe (MBF) procedure has low sensitivity to the lack of multivariate normality and homogeneity of covariance matrices. Both methods assume complete data for all subjects. In this paper, we present combination rules for the MANOVA and MBF procedures with multiply imputed datasets. These rules are illustrated by pooling the results obtained with a two-factor multivariate design after applying the two