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RhC1INH is beneficial in lowering renal ischemia/reperfusion injury in experimental models. METHODS In this placebo-controlled, double-blind, single-center trial 77 customers with persistent kidney condition were randomized to receive 50 IU/kg rhC1INH before and 4 h after optional coronary angiography or placebo. The main result was the peak change of urinary neutrophil gelatinase-associated lipocalin within 48 h, a surrogate marker of renal damage. RESULTS Median peak change of urinary neutrophil