https://www.selleckchem.com/pr....oducts/usp25-28-inhi
The activation and proliferation of naive CD4 T cells produce helper T cells, and increase the susceptible population in the presence of HIV. This may cause backward bifurcation. To verify this, we construct a simple within-host HIV model that includes the key variables, namely healthy naive CD4 T cells, helper T cells, infected CD4 T cells and virus. When the viral basic reproduction number R0 is less than unity, we show theoretically and numerically that bistability for RC less then R0 less then 1 can be caused by a bac