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This article reports the rehabilitation of an adult cleft palate patient with a totally edentulous maxilla using an implant-retained prosthesis. The purpose of this study is to evaluate the clinical efficacy of enhancing deficient interdental papilla with hyaluronic acid gel injection. Eight patients (three males and five females) were included. Patients had papillary deficiency in the upper anterior area. Prior to treatment, photographic images were taken for each patient. After the administration of a local anesthetic