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deep brain stimulation. The natural history of spinal cord cavernous malformations (SCCMs) remains relatively unclear. To investigate the natural history for hemorrhagic risks and neurological outcomes, as well as relevant predicting factors, of SCCMs. All patients between 2002 and 2019 with diagnosis of SCCMs were identified retrospectively. An observational study of patients with conservative management was performed to reveal the natural history of SCCMs. We identified 305 patients in the full cohort, including 126 patients who were c