https://www.selleckchem.com/pr....oducts/almorexant-hc
Several articles showed that statistical efficiency of multi-arm randomized clinical trials (RCTs) is much better than conventional two-arm RCTs. Multi-arm RCTs attract interest mainly when the experimental treatment regimen is not optimized or several pipelines under development exist. Breast cancer is a possible candidate disease. Our aim was to elucidate the current study designs and multiplicity adjustment methods in multi-arm RCTs. A search of the PubMed database revealed 468 articles on breast cancer RCTs published from 201