https://www.selleckchem.com/pr....oducts/mevastatin.ht
thways represent new opportunities for the development of unconventional and potentially impactful treatments for metastatic melanoma.Gastrointestinal stromal tumor (GIST) is the most common human sarcoma and arises in the gastrointestinal tract. Most GISTs are caused by activating mutations in the KIT receptor tyrosine kinase, such as the exon 11 KIT V559Δ mutation. The small molecule imatinib inhibits KIT and has been a mainstay of therapy in GIST. Unfortunately, imatinib-treated patients typically relapse, most often due to clonal

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