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Therefore, it is advisable to know if potentially efficient therapeutic levels of isoproterenol can be achieved, maintaining safe plasma levels without the untoward pharmacological impacts. The objective of the analysis is to explore the mind pharmacokinetics and biodistribution of 11C-labeled isoproterenol in rats. Practices We performed positron emission tomography (animal) brain imaging and biodistribution studies of [11C]isoproterenol. 120-min scans with arterial bloodstream sampling w