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Introduction Pharmacogenetic (PGx) implementation has lagged behind the development of drug/gene pair guidelines. Materials methods This was a prospective study assessing the integration of PGx through medication therapy management in an outpatient clinic. Variables collected included patient diagnosis, current medications, failed or discontinued medications, PGx results/recommendations, turnaround time and pre/post clinical ratings. Results A total of 91 participants completed study procedures with an average enrollment of approxima