https://www.selleckchem.com/pr....oducts/pkc-theta-inh
8 months in the LET arm (HR 0.73, P=0.137). Among patients with visceral metastases, the median PFS was significantly longer in the EVE arm (16.4 versus 9.5 months, P=0.048). The median OS was not reached in both arms. The CBR was significantly higher in the EVE arm (83% versus 62%, P=0.01. The ORR was similar between the two arms. The most common grade 3/4 adverse events in the EVE arm were neutropenia, alanine aminotransferase elevationand anaemia. EVE plus LET with ovarian-suppression resulted in longer PFS in tamoxifen
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