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Our results provide a rationale for the development of new combinatorial strategies for the treatment of SCLC.We present a heuristic procedure for determining key processing parameters (PPs) in materials-extrusion-based additive manufacturing processes. The concept relies on a design-of-experiment approach and consists of eleven "test objects" to determine the optimal combinations of key PPs values, starting with the PPs for printing the first layer and progressing to more complex geometric features, e.g., "bridges". In each of the test