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29 ms in a binary solvent of acetonitrile and chlorobenzene. The lifetime of the CS state is comparable to that of ZnTPPS4-/Li+@C60 in benzonitrile.Bioimaging is a powerful strategy for studying biological activities, which is still limited by the difficulty of distinguishing obscured signals from high background. Despite the development of various new imaging materials and methods, target signals are still likely to be submerged in spontaneous fluorescence or scattering signals. Herein, a novel two-photon excitation-process-based imaging postproc