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9-fold, P less then 0.001) were observed in high sucrose-fed flies. Esculentin-2CHa(GA3 alone did not affect levels of total thiol, reduced glutathione, glucose and catalase activity. Improved survival (1.2-1.3-fold, P less then 0.05-0.01) and longevity (1.3-fold) were observed in flies treated with the peptide (5.0 and 7.5 μmol/kg diet). Feeding on sucrose and esculentin-2CHa(1-3 (5.0 and 7.0 μmol/kg diet) for 7 days increased total thiol (2 - 3-fold, P less then 0.001) and reduced glutathione (1.6-1.8-fold, P less then 0.05) level