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To systematically review studies that examined the influence of the CYP1A2 -163CA polymorphism on the ergogenic effects of caffeine and to discuss some of the reasons for the discrepancies in findings between the studies. This review was performed in accordance with the PRISMA guidelines. The search for studies was performed through nine databases. Seventeen studies were included in the review. Based on the included studies, it seems that individuals with the AA or AC/CC genotype may experience an increase in performance following
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