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Synovial liquid WBC matter, neutrophil portion, and total protein, neutrophil myeloperoxidase, neutrophil elastase, and Coll2-1 concentrations were contrasted among remedies. Results Both lidocaine and mepivacaine caused SF changes indicative of irritation and a catabolic collagen response, nevertheless the magnitude of these changes had been much more pronounced for lidocaine. Methyl parahydroxybenzoate didn't cause any SF changes indicative of irritation. Conclusions and clinical relevance Results proposed that mepivacaine was saf