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This retrospective cohort research was carried out in an extensive care device from November 2009 to August 2014. The CRT occurrence clinically determined to have ultrasound examination had been compared between clients applying CGCD and combined 10% aqueous povidone-iodine and standard transparent dressings (PITD) after central venous catheter insertion to the internal jugular vein for ≥ 48 h. CRT had been stratified into early (within 1 week) and belated (day