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l noninvasive biomarker to predict the prognosis of HCC patients. AIM Colorectal signet-ring cell carcinomas (SRCC) are highly malignant tumours with poor prognosis that disproportionately affect younger patients. There is growing evidence of a unique set of molecular features that separate SRCC from conventional colorectal adenocarcinoma. Identification of these distinct features may have diagnostic and prognostic significance for patients and families. CDH1, which encodes E-cadherin, a cell adhesion protein, is commonly mutated in ga

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How to Repair a Bifold Door Top Pivot A bifold closet door's top pivot may be loosened and scrape the floor. You can correct this by loosening the set screw of the top bracket slightly. The pivot pin on the top is a screw made of metal that is inserted into a cap made of plastic with an lipped end that is inside the track above the door. You'll also need an screwdriver and perhaps a pair pliers. Take off the pin at the bottom. are great for saving space in a closet but they may begin to buckle or scrape t