https://www.selleckchem.com/pr....oducts/kynurenic-aci
This review aims to summarize the main pathophysiological events involved in the development of hereditary angioedema (OMIM#10610. Hereditary angioedema is a rare genetic disease inherited in an autosomal dominant manner and caused by a loss of control over the plasma contact system or kallikrein-kinin system, which results in unrestrained bradykinin generation or signaling. In patients with hereditary angioedema, BK binding to endothelial cells leads to recurrent episodes of swelling at subcutaneous or submucosal tissues that
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