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Utilizing meningioma cells plus in vitro designs, we investigated microRNA amounts in meningioma types of different grades, as well as their particular legislation. Predicated on this, we also investigated candidate miRNAs phrase in serum, and their potential as biomarkers. We discovered that miR-497~195 cluster phrase in meningioma decreases with increasing malignancy class, and therefore Cyclin D1 overexpression correlated with downregulation associated with miR-497~195 group. GATA bindin

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The relative expressions of CyclinA and CDK2 proteins and mRNA in the cervical cancer group were significantly higher than those in the control group (P less then 0.05). Pearson correlation analysis showed a positive correlation between CyclinA and CDK2 proteins and mRNA expressions. After treatment, the expressions of CyclinA, CDK2 mRNA and SCCA, CEA and VEGF were significantly lower than those before treatment (P less then 0.05). The 3-year survival rate of CyclinA and CDK2 in the high expression group was significantly lower than that