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asures to prevent COVID-19 infection and associated illness, hence should be prioritized while implementing recommendations of additional COVID-19 vaccine doses. Management of elderly patients with cancer has become a global issue. We investigated the safety and tolerability of lenvatinib in hepatocellular carcinoma (HCC) patients ≥80 years old. We retrospectively evaluated 61 HCC patients and divided them into 2 groups an elderly group (n = 13, ≥80 years old) and a younger group (n = 48, 80 years old). We compared the adverse events