https://www.selleckchem.com/pr....oducts/bgb-283-bgb28
The correlation between HR TTP and HR OS was moderate (R =0.65. 95%CI 0.08-0.81). R value was 0.04 (95%CI 0.00-0.35) between median TTP and median OS. In studies of TACE for u-HCC, the surrogate relationship of radiology-based endpoints with OS is moderate. Multiple endpoints including hepatic decompensation, macrovascular invasion and extrahepatic spread are needed for future trials comparing systemic therapies or combination of TACE with systemic therapies vs TACE alone. In studies of TACE for u-HCC, the surrogate relationship
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