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For Adults Stimulants like methylphenidate and amphetamine increase the levels of certain brain chemicals. Nonstimulants like atomoxetine or antidepressants are slower than stimulants, but they could be as effective. Comorbid conditions can impact the effectiveness to ADHD medication. The most severe symptom from any comorbid condition must be treated first. Then, the doctor must monitor whether ADHD symptoms improve. Medication Medication is the most common form of treat