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3%) initiating treatment (p=0.002). In those with HIV co-morbidity 36 (66.7%) were depressed while 35 (35.7%) were depressed among those without HIV co-morbidity (p 0.001). Among those who had poor perception of treatment outcome, 7 (87.5%) were depressed compared to 64 (44.4%) with good perception, p=0.018. Overall, predictors of depression were having poor perception about outcome of treatment (AOR 12.9; CI 95% 1.4-118.4), having HIV co-morbidity (AOR 2.9; CI 95% 1.4-6.3) and being on continuous phase of TB treatment (AOR 2.