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Syphilis continues to be a common sexually transmitted disease. To describe the epidemiologic features of patients with syphilis consulting in a Chilean sexually transmitted diseases clinic. Review of medical records of patients with positive serology for syphilis, who attended a unit of sexually transmitted diseases between 2015 and 2017. Of 266 cases, 61% were male and 74% were aged between 20 and 49 years. The highest incidence was observed in males aged between 20 and 30 years. Eighty five percent of cases were diagnosed in latent p