https://www.selleckchem.com/pr....oducts/FK-506-(Tacro
Loss of efficacy (LOE) is a well-known phenomenon associated with spinal cord stimulation (SCS) and is the leading cause of explant. Although recent advances in neuromodulation have resulted in a decreased incidence of LOE, it still occurs. Intuition suggests that when LOE ensues, switching to a different SCS therapy/platform could potentially be a viable clinical option; however, there are no data presently available to validate this theory. The primary objective was to evaluate the efficacy of SCS therapy rotation with DeR
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