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Therefore, these results indicated that the DOX-loaded, ST-SA stabilized MNCs improved the therapeutic index of DOX and would be a promising therapeutic candidate for tumor therapy.We report a method to rationally control the aspect ratio of layered double hydroxide for use as a barrier coating for food packaging films. The reconstruction of a Mg2Al-layered double oxide (LDO) in concentrated aqueous glycine solutions produces dispersions of Mg2Al-LDH nanosheets. The nanosheet thickness decreases and diameter increases with increasing reco