https://www.selleckchem.com/products/gne-049.html
The platform will be a powerful tool for crop monitoring services.Cholesterol plays two critical roles in Hedgehog signaling, a fundamental pathway in animal development and cancer it covalently modifies the Sonic hedgehog (SHH) ligand, restricting its release from producing cells, and directly activates Smoothened in responding cells. In both contexts, a membrane protein related to bacterial RND transporters regulates cholesterol Dispatched1 controls release of cholesterylated SHH, and Patched1 antagonizes Smoothened activation by chol