https://www.selleckchem.com/pr....oducts/durvalumab.ht
Isorhamnetin is a natural flavonoid widely distributed in fruits and vegetables. However, the roles of isorhamnetin involved in steroidogenesis, proliferation, and apoptosis in ovarian granulosa cells (GCs) are poorly understood. We found that isorhamnetin promoted the secretion of estrogen and inhibited the secretion of progesterone and testosterone by modulating steroidogenesis-associated proteins and mRNA such as CYP19A1, StAR, and 3β-HSD in ovarian GCs. Mechanistically, isorhamnetin stimulated the expression of the proliferating

https://www.selleckchem.com/pr....oducts/CP-690550.htm
Thus, more attention should be paid to the risk of DHTR redevelopment by repeated transfusions.We report a case of Erdheim-Chester disease (ECD) complicated with central diabetes insipidus that was refractory to several treatments. A 58-year-old female suffered from fatigue, fever, thirst, polyuria, leg pain, xanthoma of her upper eyelids, and disturbance of consciousness. Computed tomography (CT) imaging showed infiltration of perivascular soft tissue surrounding the aorta, hydronephrosis, and sclerotic lesions of the femurs and tibi