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The overall rate of complete response in groups A and B were 56.0% and 33.3% (P = 0.001), respectively. Group A had higher complete response rate than group B in the subgroup of BCLC B with tumor less then 3 cm (57.9% vs. 21.1%; P = 0.02 and subgroup of feeding artery ≥0.9 mm (55.2% vs. 30.9%; P = 0.014). There were fewer major complications in group A compared with group B (0% vs. 6.9%, P = 0.018). CONCLUSION TACE with 100-300 μm DEB is associated with better initial treatment response and fewer major complications compared with 300-
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