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01). The wild-type cases had a longer survival, compared with mutant GCs, especially in patients without lymph node metastases, despite the high depth of tumor infiltration ( = 0.01). The Dukes-MAC-like staging system was proved to have the most significant independent prognostic value ( 0.01). The statistical correlations proved that gene mutations in exon 7 might induce knockdown of Maspin, but wild-type p53 can partially restore nuclear Maspin expression and decrease the metastatic potential of gastric adenocarcinoma cells. Downre