https://interleukinsreceptor.c....om/index.php/evaluat
A macrophage-depleting reagent, clodronate, had been coapplied into AAV-treated mice to examine crosstalk between beta cells and macrophages. RESULTS PlGF is exclusively produced by beta cells into the adult mouse pancreas. Furthermore, PlGF phrase in beta cells had been dramatically increased during pregnancy. Intraductal infusion of AAV-RIP-shPlGF especially knocked down PlGF in beta cells, resulting in affected beta-cell p