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Therefore, the hydrophobic support immobilizes higher amounts of TLL and the hydrophilic support keeps the enzyme hyperactivated. Last, due to the stronger interactions of TLL with hydrophobic surfaces, the hydrophobic support offers better preservation of enzyme activity in repeated cycles (76% of activity retained after three cycles versus 50% for the hydrophilic support).Sulfobetaine, a type of zwitterionic polymer, is highly biocompatible with temperature responsiveness of the upper critical solution temperature (UCST) type. The obje