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In logistic regression models, odds of ≥50% obstruction were significantly higher at the tongue base (odds ratio, 2.77; 95% CI, 1.04-7.39) after adjustment for age, sex, obesity, previous adenotonsillectomy, and syndrome. No difference was noted at the adenoid, velum, lateral wall, or supraglottis. POSA was associated with higher odds of obstruction on DISE at the tongue base but not at other levels. POSA was associated with higher odds of obstruction on DISE at the tongue base but not at other levels. Cancer patients tend to prefer or