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Network analysis further suggested neuro-immunological changes in mothers. (4) Conclusions The results confirm the roles of several hypothesized major pathways in parental care, whereas novel pathways are also proposed. Next to breast cancer, advanced stage metastatic colon cancer represents a major cause for mortality in women. Germline or somatic mutations in tumor suppressor genes or in DNA mismatch repair genes represent risk factors for genetic predisposition of colon cancer that are also detectable in sporadic colon cancer. Co