https://survivinsignal.com/ind....ex.php/high-performa
Curdlan, yeast-b and zymosan re-polarized M(IL-4) macrophages towards an M1-like phenotype, in specific showing enhanced gene appearance of CCR7, ICAM1 and CD80, and release of TNF-α and IL-6. Notably, differential gene appearance, path analysis also protein expressions demonstrated that M(IL-4) macrophages treated with curdlan, yeast-b or zymosan demonstrated enhanced production of chemo-attractants, such as CCL3, CCL4, and CXCL8, which subscribe to recruitm