https://kinasepathway.com/2024..../12/13/teenage-datin
In this research, we show that MMP-10 was upregulated when you look at the kidneys and predominantly localized in the tubular epithelium in several models of AKI induced by ischemia/reperfusion (IR) or cisplatin. Overexpression of exogenous MMP-10 ameliorated AKI, manifested by diminished serum creatinine, bloodstream urea nitrogen, tubular damage and apoptosis, and enhanced tubular regeneration. Conversely, knockdown of endogenous MMP-10 expression aggravated kidney injury. Interestingl
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