https://www.selleckchem.com/pr....oducts/bgj398-nvp-bg
SaRpAMP exhibited potent antibacterial activity comparable to piscidin 1, a powerful positive control. Its antimicrobial activity against fungus C. albicans was relatively weak. The antimicrobial activity of SaRpAMP was not diminished by heat treatment and changes in pH but was abolished by proteolytic enzyme digestion. Membrane permeability assays suggested that SaRpAMP interacts with both the outer and inner bacterial membranes. This was consistent with the results of lipid titration and quenching of Trp fluorescence that de

https://www.selleckchem.com/pr....oducts/Clofarabine.h
Sex steroids could explain the course of multiple sclerosis (MS) in pregnancy. To compare the annualized relapse rate (ARR) 12 weeks post-partum in women treated with nomegestrol acetate (NOMAc) and 17-beta-estradiol (E2) versus placebo. POPARTMUS is a randomized, proof-of-concept trial in women with MS, receiving oral NOMAc 10 mg/day and transdermal estradiol 75 µg/week, or placebo. Recruitment was stopped prematurely due to slow inclusions (  = 202). No treatment effect was observed on ARR after 12 weeks (sex steroids = 0.90 (0.58