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NF vs SF group were compared and expressed as median [interquartile range], for the left anterior descending 10 [7-11] vs 21 [8-33];p= 0.016; circumflex 9 [4-13] vs 14 [11-30]; p= 0.012 and right coronary artery 5 [3-11] vs 13 [8-26]; p=0.009. The DM showed the feasibility of measuring coronary blood flow with precision, consistency and reproducible in a standard coronary angiogram, showing the additional capability to differentiate between NF and SF in chest pain patients with normal coronary arteries. (Arq Bras Cardiol. 2020; 115(3