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In order to further validate the big event of mmi-DIGIRR and its own expression amounts in several areas of fish, qRT-PCR is carried out. The results showed DIGIRR has actually significant expression amounts in liver, skin and muscle while phrase levels in heart tend to be reduced. The LPS-induced NF-κB activation had been inhibited by overexpression of DIGIRR substantially. In closing, the evolution and purpose of mmi-DIGIRR were comprehensively analyzed in this re
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