https://www.selleckchem.com/pr....oducts/mk-5108-vx-68
The same laboratory tests were repeated after 4, 7, and 30 days during steroid therapy. Plasma SIRT-1 increased significantly during steroid administration. Plasma sclerostin did not change significantly. There was a significant linear negative correlation between changes in SIRT-1 levels and sclerostin throughout the study. In a multiple regression model, changes of plasma sclerostin induced by steroid therapy explained the largest part of variance of respective changes of plasma SIRT-1. Plasma SIRT-1 increase during high-dose c
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