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Proper case selection is important for using this procedure. Copyright © 2019 Journal of Cutaneous and Aesthetic Surgery.In recent years, autologous fibroblast injections or plasma gel filler applications have been used in the treatment of facial contour deformities. In this case report, we describe a new method of autologous filler material derived from cultured dermal fibroblast and plasma gel. The plasma gel, which is the bioskeleton of the filler, is prepared from the patient's plasma, which provides a dense environment for a three