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05). Further multiple regression analysis indicated, in addition to the correlations between BMI and ΔSBP and ΔDBP values in both sexes (all p.001), BMI was also associated with MoCA and lower UPDRS motor scores in male patients and lower HAMD scores in female patients. Our study suggests that there are significant sex differences in the prevalence of underweight, BMI, and factors associated with underweight and BMI among de novo PD patients. Our study suggests that there are significant sex differences in the prevalence o