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For the ROC analysis, both relative cerebral blood flow of lesion (rCBF-L) and relative cerebral blood flow of perilesional edema (rCBF-PE) had good diagnostic performance for discriminating non-neoplastic from neoplastic lesions, with an AUC of 0.994 and 0.846, respectively. 3D-pCASL may contribute to differentiation of non-neoplastic from neoplastic lesions. 3D-pCASL may contribute to differentiation of non-neoplastic from neoplastic lesions.Previous studies have suggested an association between infection with herpes simplex virus (H
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