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[Box see text].The aim of this paper is to describe the figure of the Italian surgeon Iginio Tansini (1855-1943), who was full professor of surgery and director of the Department of Surgery at the University of Pavia (1903-1931). In that period, he modernized the School of Surgery founded by Antonio Scarpa (1752-1832) in the previous century; he introduced the experimental method in the discipline. One of his major contributions was an innovative technique of mastectomy followed by plastic reconstruction with myocutaneous flap.