https://www.selleckchem.com/pr....oducts/ripasudil-k-1
No individual menstrual, reproductive, menopausal, or estrogen replacement variable was associated with risk of incident dementia after age 90 years. However, women with a high endogenous estrogen exposure index (summarizing exposure from menarche to menopause) had a non-significant 25% lower risk (HR = 0.75, 95% confidence interval 0.53-1.06).Conclusions Prior exposure to estrogen, endogenous or exogenous, had little effect on risk of dementia in the 10th decade of life.Purpose A strong, well-established non-linear relationship