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s cases of angular momentum couplings that are specific for each reaction channel; (5) finally, the method can be extended to reaction mechanisms of redox, acid-base, and other important condensed phase reactions.The ability to target specific proteins for degradation may open a new door toward developing therapeutics. Although effort in chemistry is essential for advancing this modality, i.e., one needs to generate proteolysis targeting chimeras (bifunctional molecules, also referred to as PROTACS) or "molecular glues" to accelerate pr