https://www.selleckchem.com/pr....oducts/n-nitroso-n-m
Area under the concentration-time curves (AUCs) were extrapolated from time 0 to infinity (AUC0→∞). Elimination rate constant (Ke) and elimination half-life (t1/2e) were also estimated. RESULTS Pharmacokinetic parameters of the control group (amikacin only) vis-a-vis the test group were as follows Cmax; 42.4 μmol/L vs 19.0 μmol/L, AUC0→∞; 84.9 μmol/L/h vs 41.4 μmol/L/h, Ke; 0.12 hours-1 vs 0.24 hours-1, and t1/2; 5.87 hours vs 2.88 hours, respectively. CONCLUSION This study suggests possible interaction between aminophyll
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